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Levosimendan improves exercise performance in patients with advanced chronic heart failure.

ABSTRACT: AIMS:Cardiopulmonary exercise test (CPET) provides parameters such as peak VO2 and ventilation/CO2 production (VE/VCO2) slope, which are strong prognostic predictors in patients with stable advanced chronic heart failure (ADHF). The study aim was to evaluate the effects of the inodilator levosimendan on CPET in patients with ADHF under stable clinical conditions. METHODS AND RESULTS:We enrolled patients with ADHF (peak VO2?

SUBMITTER: Mushtaq S 

PROVIDER: S-EPMC5042087 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature

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Levosimendan improves exercise performance in patients with advanced chronic heart failure.

Mushtaq Saima S   Andreini Daniele D   Farina Stefania S   Salvioni Elisabetta E   Pontone Gianluca G   Sciomer Susanna S   Volpato Valentina V   Agostoni Piergiuseppe P  

ESC heart failure 20150813 3

<h4>Aims</h4>Cardiopulmonary exercise test (CPET) provides parameters such as peak VO<sub>2</sub> and ventilation/CO<sub>2</sub> production (VE/VCO<sub>2</sub>) slope, which are strong prognostic predictors in patients with stable advanced chronic heart failure (ADHF). The study aim was to evaluate the effects of the inodilator levosimendan on CPET in patients with ADHF under stable clinical conditions.<h4>Methods and results</h4>We enrolled patients with ADHF (peak VO<sub>2</sub> < 12 mL/min/kg  ...[more]

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