Process-based design of dynamical biological systems.
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ABSTRACT:
SUBMITTER: Tanevski J
PROVIDER: S-EPMC5043446 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Publications
Process-based design of dynamical biological systems.
Tanevski Jovan J Todorovski Ljupčo L Džeroski Sašo S
Scientific reports 20160930
The computational design of dynamical systems is an important emerging task in synthetic biology. Given desired properties of the behaviour of a dynamical system, the task of design is to build an in-silico model of a system whose simulated be- haviour meets these properties. We introduce a new, process-based, design methodology for addressing this task. The new methodology combines a flexible process-based formalism for specifying the space of candidate designs with multi-objective optimization ...[more]
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