Ontology highlight
ABSTRACT:
SUBMITTER: Douzi B
PROVIDER: S-EPMC5048182 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Douzi Badreddine B Brunet Yannick R YR Spinelli Silvia S Lensi Valentine V Legrand Pierre P Blangy Stéphanie S Kumar Anant A Journet Laure L Cascales Eric E Cambillau Christian C
Scientific reports 20161004
The Type VI secretion system (T6SS) is a versatile machine that delivers toxins into either eukaryotic or bacterial cells. It thus represents a key player in bacterial pathogenesis and inter-bacterial competition. Schematically, the T6SS can be viewed as a contractile tail structure anchored to the cell envelope. The contraction of the tail sheath propels the inner tube loaded with effectors towards the target cell. The components of the contracted tail sheath are then recycled by the ClpV AAA<s ...[more]