Ontology highlight
ABSTRACT:
SUBMITTER: Cohen MS
PROVIDER: S-EPMC5049503 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Cohen Myron S MS Chen Ying Q YQ McCauley Marybeth M Gamble Theresa T Hosseinipour Mina C MC Kumarasamy Nagalingeswaran N Hakim James G JG Kumwenda Johnstone J Grinsztejn Beatriz B Pilotto Jose H S JH Godbole Sheela V SV Chariyalertsak Suwat S Santos Breno R BR Mayer Kenneth H KH Hoffman Irving F IF Eshleman Susan H SH Piwowar-Manning Estelle E Cottle Leslie L Zhang Xinyi C XC Makhema Joseph J Mills Lisa A LA Panchia Ravindre R Faesen Sharlaa S Eron Joseph J Gallant Joel J Havlir Diane D Swindells Susan S Elharrar Vanessa V Burns David D Taha Taha E TE Nielsen-Saines Karin K Celentano David D DD Essex Max M Hudelson Sarah E SE Redd Andrew D AD Fleming Thomas R TR
The New England journal of medicine 20160718 9
<h4>Background</h4>An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked infections caused by human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. ART was then offered to all patients with HIV-1 infection (index participants). The study included more than 5 years of follow-up to assess the durability of such therapy for the prevention of HIV-1 transmission.<h4>Me ...[more]