Transforming clinical microbiology with bacterial genome sequencing.
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ABSTRACT:
SUBMITTER: Didelot X
PROVIDER: S-EPMC5049685 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Publications
Transforming clinical microbiology with bacterial genome sequencing.
Didelot Xavier X Bowden Rory R Wilson Daniel J DJ Peto Tim E A TEA Crook Derrick W DW
Nature reviews. Genetics 20120807 9
Whole-genome sequencing of bacteria has recently emerged as a cost-effective and convenient approach for addressing many microbiological questions. Here, we review the current status of clinical microbiology and how it has already begun to be transformed by using next-generation sequencing. We focus on three essential tasks: identifying the species of an isolate, testing its properties, such as resistance to antibiotics and virulence, and monitoring the emergence and spread of bacterial pathogen ...[more]
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