Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluoxetine.
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ABSTRACT:
SUBMITTER: Pei S
PROVIDER: S-EPMC5050550 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
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Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluoxetine.
Pei Siran S Liu Li L Zhong Zhaomin Z Wang Han H Lin Shuo S Shang Jing J
Scientific reports 20161005
Fluoxetine is widely used to treat depression, including depression in pregnant and postpartum women. Studies suggest that fluoxetine may have adverse effects on offspring, presumably through its action on various serotonin receptors (HTRs). However, definitive evidence and the underlying mechanisms are largely unavailable. As initial steps towards establishing a human cellular and animal model, we analyzed the expression patterns of several HTRs through the differentiation of human induced plur ...[more]
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