Ontology highlight
ABSTRACT:
SUBMITTER: Green DJ
PROVIDER: S-EPMC5052091 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Green D J DJ Bensinger W I WI Holmberg L A LA Gooley T T Till B G BG Budde L E LE Pagel J M JM Frayo S L SL Roden J E JE Hedin L L Press O W OW Gopal A K AK
Bone marrow transplantation 20160523 10
Chemotherapeutic agents without cross-resistance to prior therapies may enhance PBSC collection and improve patient outcomes by exacting a more potent direct antitumor effect before autologous stem cell transplant. Bendamustine has broad clinical activity in transplantable lymphoid malignancies, but concern remains over the potential adverse impact of this combined alkylator-nucleoside analog on stem cell mobilization. We performed a prospective, nonrandomized phase II study including 34 patient ...[more]