Ontology highlight
ABSTRACT:
SUBMITTER: Dow XY
PROVIDER: S-EPMC5052452 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Dow Ximeng Y XY DeWalt Emma L EL Sullivan Shane Z SZ Schmitt Paul D PD Ulcickas James R W JRW Simpson Garth J GJ
Biophysical journal 20161001 7
Nonlinear optical Stokes ellipsometric (NOSE) microscopy was demonstrated for the analysis of collagen-rich biological tissues. NOSE is based on polarization-dependent second harmonic generation imaging. NOSE was used to access the molecular-level distribution of collagen fibril orientation relative to the local fiber axis at every position within the field of view. Fibril tilt-angle distribution was investigated by combining the NOSE measurements with ab initio calculations of the predicted mol ...[more]