Unknown

Dataset Information

0

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.

ABSTRACT:

SUBMITTER: Gharahkhani P 

PROVIDER: S-EPMC5052458 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.

Gharahkhani Puya P   Fitzgerald Rebecca C RC   Vaughan Thomas L TL   Palles Claire C   Gockel Ines I   Tomlinson Ian I   Buas Matthew F MF   May Andrea A   Gerges Christian C   Anders Mario M   Becker Jessica J   Kreuser Nicole N   Noder Tania T   Venerito Marino M   Veits Lothar L   Schmidt Thomas T   Manner Hendrik H   Schmidt Claudia C   Hess Timo T   Böhmer Anne C AC   Izbicki Jakob R JR   Hölscher Arnulf H AH   Lang Hauke H   Lorenz Dietmar D   Schumacher Brigitte B   Hackelsberger Andreas A   Mayershofer Rupert R   Pech Oliver O   Vashist Yogesh Y   Ott Katja K   Vieth Michael M   Weismüller Josef J   Nöthen Markus M MM   Attwood Stephen S   Barr Hugh H   Chegwidden Laura L   de Caestecker John J   Harrison Rebecca R   Love Sharon B SB   MacDonald David D   Moayyedi Paul P   Prenen Hans H   Watson R G Peter RGP   Iyer Prasad G PG   Anderson Lesley A LA   Bernstein Leslie L   Chow Wong-Ho WH   Hardie Laura J LJ   Lagergren Jesper J   Liu Geoffrey G   Risch Harvey A HA   Wu Anna H AH   Ye Weimin W   Bird Nigel C NC   Shaheen Nicholas J NJ   Gammon Marilie D MD   Corley Douglas A DA   Caldas Carlos C   Moebus Susanne S   Knapp Michael M   Peters Wilbert H M WHM   Neuhaus Horst H   Rösch Thomas T   Ell Christian C   MacGregor Stuart S   Pharoah Paul P   Whiteman David C DC   Jankowski Janusz J   Schumacher Johannes J  

The Lancet. Oncology 20160812 10

<h4>Background</h4>Oesophageal adenocarcinoma represents one of the fastest rising cancers in high-income countries. Barrett's oesophagus is the premalignant precursor of oesophageal adenocarcinoma. However, only a few patients with Barrett's oesophagus develop adenocarcinoma, which complicates clinical management in the absence of valid predictors. Within an international consortium investigating the genetics of Barrett's oesophagus and oesophageal adenocarcinoma, we aimed to identify novel gen  ...[more]

Similar Datasets

Unknown Subtypes of Barrett's oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis.
| S-EPMC6565505 | biostudies-literature
Unknown 'Missed' oesophageal adenocarcinoma and high-grade dysplasia in Barrett's oesophagus patients: A large population-based study.
| S-EPMC5987274 | biostudies-literature
Unknown Systematic review with meta-analysis: prevalence of prior and concurrent Barrett's oesophagus in oesophageal adenocarcinoma patients.
| S-EPMC7293564 | biostudies-literature
Unknown Demographic and phenotypic features of 70 families segregating Barrett's oesophagus and oesophageal adenocarcinoma.
| S-EPMC1735581 | biostudies-literature
Unknown Pathogenesis and progression of oesophageal adenocarcinoma varies by prior diagnosis of Barrett's oesophagus.
| S-EPMC5129823 | biostudies-literature
Unknown Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus.
| S-EPMC4893117 | biostudies-literature
Unknown Circulating microRNAs as potential biomarkers to detect transformation of Barrett's oesophagus to oesophageal adenocarcinoma.
| S-EPMC5689485 | biostudies-literature
Unknown Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma.
| S-EPMC5296402 | biostudies-literature
Unknown Systematic review with meta-analysis: the effects of family history on the risk of Barrett's oesophagus and oesophageal adenocarcinoma.
| S-EPMC9292032 | biostudies-literature
Unknown Barrett's oesophagus and oesophageal cancer following oesophageal atresia repair: a systematic review.
| S-EPMC8405903 | biostudies-literature