Ontology highlight
ABSTRACT:
SUBMITTER: Gharahkhani P
PROVIDER: S-EPMC5052458 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Gharahkhani Puya P Fitzgerald Rebecca C RC Vaughan Thomas L TL Palles Claire C Gockel Ines I Tomlinson Ian I Buas Matthew F MF May Andrea A Gerges Christian C Anders Mario M Becker Jessica J Kreuser Nicole N Noder Tania T Venerito Marino M Veits Lothar L Schmidt Thomas T Manner Hendrik H Schmidt Claudia C Hess Timo T Böhmer Anne C AC Izbicki Jakob R JR Hölscher Arnulf H AH Lang Hauke H Lorenz Dietmar D Schumacher Brigitte B Hackelsberger Andreas A Mayershofer Rupert R Pech Oliver O Vashist Yogesh Y Ott Katja K Vieth Michael M Weismüller Josef J Nöthen Markus M MM Attwood Stephen S Barr Hugh H Chegwidden Laura L de Caestecker John J Harrison Rebecca R Love Sharon B SB MacDonald David D Moayyedi Paul P Prenen Hans H Watson R G Peter RGP Iyer Prasad G PG Anderson Lesley A LA Bernstein Leslie L Chow Wong-Ho WH Hardie Laura J LJ Lagergren Jesper J Liu Geoffrey G Risch Harvey A HA Wu Anna H AH Ye Weimin W Bird Nigel C NC Shaheen Nicholas J NJ Gammon Marilie D MD Corley Douglas A DA Caldas Carlos C Moebus Susanne S Knapp Michael M Peters Wilbert H M WHM Neuhaus Horst H Rösch Thomas T Ell Christian C MacGregor Stuart S Pharoah Paul P Whiteman David C DC Jankowski Janusz J Schumacher Johannes J
The Lancet. Oncology 20160812 10
<h4>Background</h4>Oesophageal adenocarcinoma represents one of the fastest rising cancers in high-income countries. Barrett's oesophagus is the premalignant precursor of oesophageal adenocarcinoma. However, only a few patients with Barrett's oesophagus develop adenocarcinoma, which complicates clinical management in the absence of valid predictors. Within an international consortium investigating the genetics of Barrett's oesophagus and oesophageal adenocarcinoma, we aimed to identify novel gen ...[more]