Ontology highlight
ABSTRACT:
SUBMITTER: Paquin-Proulx D
PROVIDER: S-EPMC5053825 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Paquin-Proulx D D Ching C C Vujkovic-Cvijin I I Fadrosh D D Loh L L Huang Y Y Somsouk M M Lynch S V SV Hunt P W PW Nixon D F DF SenGupta D D
Mucosal immunology 20160406 1
Invariant natural killer T (iNKT) cells are innate-like T cells that respond to lipid antigens presented by CD1d. These immunoregulatory cells have the capacity for rapid cytokine release after antigen recognition and are essential for the activation of multiple arms of the immune response. HIV-1 infection is associated with iNKT cell depletion in the peripheral blood; however, their role in the gastrointestinal-associated lymphoid tissue (GALT) is less well studied. Our results show that iNKT c ...[more]