Stem Cells in Bone Regeneration.
Ontology highlight
ABSTRACT:
SUBMITTER: Walmsley GG
PROVIDER: S-EPMC5053855 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
Stem Cells in Bone Regeneration.
Walmsley Graham G GG Ransom Ryan C RC Zielins Elizabeth R ER Leavitt Tripp T Flacco John S JS Hu Michael S MS Lee Andrew S AS Longaker Michael T MT Wan Derrick C DC
Stem cell reviews and reports 20161001 5
Bone has the capacity to regenerate and repair itself. However, this capacity may be impaired or lost depending on the size of the defect or the presence of certain disease states. In this review, we discuss the key principles underlying bone healing, efforts to characterize bone stem and progenitor cell populations, and the current status of translational and clinical studies in cell-based bone tissue engineering. Though barriers to clinical implementation still exist, the application of stem a ...[more]
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