Structural and functional analysis of NS1 and NS2 proteins of H1N1 subtype.
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ABSTRACT:
SUBMITTER: Salahuddin P
PROVIDER: S-EPMC5054132 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
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Structural and functional analysis of NS1 and NS2 proteins of H1N1 subtype.
Salahuddin Parveen P Khan Asad U AU
Genomics, proteomics & bioinformatics 20100901 3
Influenza A virus (H1N1), a genetic reassortment of endemic strains of human, avian and swine flu, has crossed species barrier to human and apparently acquired the capability of human to human transmission. Some strains of H5N1 subtype are highly virulent because NS1 protein inhibits antiviral interferon α/β production. Another protein NS2 mediates export of viral ribonucleoprotein from nucleus to the cytoplasm through export signal. In this paper, we have studied structure-function relationship ...[more]
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