Dataset Information

Implementation of Arithmetic and Nonarithmetic Functions on a Label-free and DNA-based Platform.

ABSTRACT: A series of complex logic gates were constructed based on graphene oxide and DNA-templated silver nanoclusters to perform both arithmetic and nonarithmetic functions. For the purpose of satisfying the requirements of progressive computational complexity and cost-effectiveness, a label-free and universal platform was developed by integration of various functions, including half adder, half subtractor, multiplexer and demultiplexer. The label-free system avoided laborious modification of biomolecules. The designed DNA-based logic gates can be implemented with readout of near-infrared fluorescence, and exhibit great potential applications in the field of bioimaging as well as disease diagnosis.

SUBMITTER: Wang K

PROVIDER: S-EPMC5054380 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature

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Publications

Implementation of Arithmetic and Nonarithmetic Functions on a Label-free and DNA-based Platform.

Wang Kun K He Mengqi M Wang Jin J He Ronghuan R Wang Jianhua J

Scientific reports 20161007

A series of complex logic gates were constructed based on graphene oxide and DNA-templated silver nanoclusters to perform both arithmetic and nonarithmetic functions. For the purpose of satisfying the requirements of progressive computational complexity and cost-effectiveness, a label-free and universal platform was developed by integration of various functions, including half adder, half subtractor, multiplexer and demultiplexer. The label-free system avoided laborious modification of biomolecu ...[more]

PMID: 27713517

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Project description:Background: This paper presents an efficient two-dimensional (2-D) finite impulse response (FIR) filter using block processing for two different symmetries. Architectures for a general filter (without symmetry) and two symmetrical filters (diagonal and quadrantal symmetry) are implemented. The proposed architectures need fewer multipliers because of the symmetry of the filter coefficients. Methods: A distributed arithmetic (DA)- based multiplication method is used in the proposed architecture. A dual-port memory-based lookup table (DP-MLUT) is used in the multiplication instead of lookup-table (LUT) to reduce the area and power of the FIR filter. The filter's throughput is increased by using block processing. Memory reuse and memory sharing methods are introduced, which reduces the need for many registers and hence the circuit complexity. The architectures are written in Verilog Hardware Description Language and synthesized using Genus Synthesis tool-19.1 in 45nm technology with a generic library of Cadence vendor constraints. The synthesis tool generates the area, delay, and power reports. Power consumption of architectures is calculated with an image size of 64 X 64 and at 20 MHz frequency. Results: Compared to existing architectures, the synthesis results show improvements in power, area, area delay product (ADP), and power delay product (PDP). The proposed MLUT-based 2-D block Quadrantal Symmetry Filter (QSF) for length 8 with block size 4 consumes 58.94% less power, occupies 59.5% less area, 48.44% less ADP and 47.78% less PDP compared to best existing methods. Conclusions: A novel DA-based 2-D block FIR filter architecture with various symmetries is realized. Symmetry is incorporated into the filter coefficients to minimize the number of multipliers. The LUT size is optimized by odd multiples or even multiples storage techniques. Also, the overall area of the architecture is decreased by DP-LUT-based multipliers. The proposed filter architecture is area-power-efficient. It is best suited for applications that have fixed coefficients.

Dataset Information

Implementation of Arithmetic and Nonarithmetic Functions on a Label-free and DNA-based Platform.

Publications

Implementation of Arithmetic and Nonarithmetic Functions on a Label-free and DNA-based Platform.

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