Dataset Information

Association of Patient Age at Gastric Bypass Surgery With Long-term All-Cause and Cause-Specific Mortality.

ABSTRACT: Bariatric surgery is effective in reducing all-cause and cause-specific long-term mortality. Whether the long-term mortality benefit of surgery applies to all ages at which surgery is performed is not known.To examine whether gastric bypass surgery is equally effective in reducing mortality in groups undergoing surgery at different ages.All-cause and cause-specific mortality rates and hazard ratios (HRs) were estimated from a retrospective cohort within 4 categories defined by age at surgery: younger than 35 years, 35 through 44 years, 45 through 54 years, and 55 through 74 years. Mean follow-up was 7.2 years. Patients undergoing gastric bypass surgery seen at a private surgical practice from January 1, 1984, through December 31, 2002, were studied. Data analysis was performed from June 12, 2013, to September 6, 2015. A cohort of 7925 patients undergoing gastric bypass surgery and 7925 group-matched, severely obese individuals who did not undergo surgery were identified through driver license records. Matching criteria included year of surgery to year of driver license application, sex, 5-year age groups, and 3 body mass index categories.Roux-en-Y gastric bypass surgery.All-cause and cause-specific mortality compared between those undergoing and not undergoing gastric bypass surgery using HRs.Among the 7925 patients who underwent gastric bypass surgery, the mean (SD) age at surgery was 39.5?(10.5) years, and the mean (SD) presurgical body mass index was 45.3?(7.4). Compared with 7925 matched individuals not undergoing surgery, adjusted all-cause mortality after gastric bypass surgery was significantly lower for patients 35 through 44 years old (HR, 0.54; 95% CI, 0.38-0.77), 45 through 54 years old (HR, 0.43; 95% CI, 0.30-0.62), and 55 through 74 years old (HR, 0.50; 95% CI, 0.31-0.79; P?

SUBMITTER: Davidson LE

PROVIDER: S-EPMC5055061 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature

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Association of Patient Age at Gastric Bypass Surgery With Long-term All-Cause and Cause-Specific Mortality.

Davidson Lance E LE Adams Ted D TD Kim Jaewhan J Jones Jessica L JL Hashibe Mia M Taylor David D Mehta Tapan T McKinlay Rodrick R Simper Steven C SC Smith Sherman C SC Hunt Steven C SC

JAMA surgery 20160701 7

<h4>Importance</h4>Bariatric surgery is effective in reducing all-cause and cause-specific long-term mortality. Whether the long-term mortality benefit of surgery applies to all ages at which surgery is performed is not known.<h4>Objective</h4>To examine whether gastric bypass surgery is equally effective in reducing mortality in groups undergoing surgery at different ages.<h4>Design, setting, and participants</h4>All-cause and cause-specific mortality rates and hazard ratios (HRs) were estimate ...[more]

PMID: 26864395

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Dataset Information

Association of Patient Age at Gastric Bypass Surgery With Long-term All-Cause and Cause-Specific Mortality.

Publications

Association of Patient Age at Gastric Bypass Surgery With Long-term All-Cause and Cause-Specific Mortality.

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