Dataset Information

Antibiotic Treatment and Length of Hospital Stay in Relation to Delivery Mode and Prematurity.

ABSTRACT:

Aim

To investigate how 1) maternal delivery mode and 2) prematurity in infants are associated to antibiotic treatment and length of hospital stay.

Methods

Women having given birth and infants 0-12 months discharged from hospital between July 2005 and November 2011 were identified from the Swedish National Patient Register. Medical records were reviewed for 203 women and 527 infants. The risk ratio (RR) between antibiotic treatment and 1) delivery mode in women; 2) prematurity in infants was calculated. Length of stay and days of antibiotic therapy were compared by Wilcoxon rank-sum test.

Results

Women: There was an association between emergency caesarean section (CS) and antibiotic treatment (RR 5.0 95% confidence interval (CI) 2.2-11.5), but not for elective CS. Length of stay was longer for CS (emergency and elective) compared to vaginal delivery (p<0.01). Infants: RR for antibiotic treatment in preterm compared to term infants was 1.4 (95% CI 1.0-1.9). Length of stay (p<0.01), but not days of therapy (p = 0.17), was higher in preterm compared to term infants.

Conclusion

We found that emergency CS increased the probability of maternal antibiotic treatment during hospitalisation, but no difference was found between term and preterm infants. The results are well aligned with current guidelines and may be considered in future studies on the effects of antibiotics.

SUBMITTER: Ahlen KM

PROVIDER: S-EPMC5055307 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Publications

Antibiotic Treatment and Length of Hospital Stay in Relation to Delivery Mode and Prematurity.

Ahlén Katia M KM Örtqvist Anne K AK Gong Tong T Wallas Alva A Ye Weimin W Lundholm Cecilia C Almqvist Catarina C

PloS one 20161007 10

<h4>Aim</h4>To investigate how 1) maternal delivery mode and 2) prematurity in infants are associated to antibiotic treatment and length of hospital stay.<h4>Methods</h4>Women having given birth and infants 0-12 months discharged from hospital between July 2005 and November 2011 were identified from the Swedish National Patient Register. Medical records were reviewed for 203 women and 527 infants. The risk ratio (RR) between antibiotic treatment and 1) delivery mode in women; 2) prematurity in i ...[more]

PMID: 27716779

Similar Datasets

Project description:BackgroundThe literature about the impact of congenital heart disease (CHD) on the length of hospital stay after delivery is limited, and nonexisting in a country with free and equal access to healthcare. We aimed to examine the hypothesis that Danish women with CHD have a longer hospital stay after delivery compared to women without CHD. Secondarily, we aimed to examine the hypothesis that cesarean section modifies the association.MethodsThe study was a national cohort study using Danish nationwide registers in 1997-2014. Maternal CHD was categorized as simple, moderate, or complex CHD. The comparison group consisted of women without CHD. Outcome of interest was length of hospital stay after delivery registered in complete days. Mode of delivery was categorized as cesarean section or vaginal delivery. Data was analyzed using a generalized linear model with a Poisson distribution.ResultsWe included 939,678 births among 551,119 women. Women without CHD were on average admitted to the hospital for 3.6 (SD 3.7) days, whereas women with simple, moderate, and complex CHD were admitted for 3.9 (SD 4.4), 4.0 (SD 3.8) and 5.1 (SD 6.7) days, respectively. The adjusted length of hospital stay after delivery was 12% (relative ratio (RR) = 1.12, 95% confidence interval (CI) 1.07-1.18), 14% (RR = 1.14, 95% CI: 1.07-1.21), and 45% (RR = 1.45, 95% CI: 1.24-1.70) longer among women with simple, moderate, and complex CHD, respectively, compared to women without CHD. The association between maternal CHD and length of hospital stay was not modified by mode of delivery (p-value of interaction = 0.62). Women who gave birth by cesarean section were on average admitted to the hospital for 2.7 days longer compared to women with vaginal delivery.ConclusionThe hospital stay after delivery was significantly longer among women with CHD as compared to women without CHD. Further, higher complexity of CHD was associated with longer length of stay. Cesarean section did not modify the association.

Dataset Information

Antibiotic Treatment and Length of Hospital Stay in Relation to Delivery Mode and Prematurity.

Aim

Methods

Results

Conclusion

Publications

Antibiotic Treatment and Length of Hospital Stay in Relation to Delivery Mode and Prematurity.

Similar Datasets

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