Ontology highlight
ABSTRACT:
SUBMITTER: Surendran P
PROVIDER: S-EPMC5056636 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Nature genetics 20160912 10
High blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we genotyped 242,296 rare, low-frequency and common genetic variants in up to 192,763 individuals and used ∼155,063 samples for independent replication. We identified 30 new blood pressure- or hypertension-associated genetic regions in the general population, including 3 rare miss ...[more]