Global disruption of degree rank order: a hallmark of chronic pain.
Ontology highlight
ABSTRACT:
SUBMITTER: Mansour A
PROVIDER: S-EPMC5057075 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
Global disruption of degree rank order: a hallmark of chronic pain.
Mansour Ali A Baria Alex T AT Tetreault Pascal P Vachon-Presseau Etienne E Chang Pei-Ching PC Huang Lejian L Apkarian A Vania AV Baliki Marwan N MN
Scientific reports 20161011
Chronic pain remains poorly understood; yet it is associated with the reorganization of the nervous system. Here, we demonstrate that a unitary global measure of functional connectivity, defined as the extent of degree rank order disruption, k<sub>D</sub>, identifies the chronic pain state. In contrast, local degree disruption differentiates between chronic pain conditions. We used resting-state functional MRI data to analyze the brain connectome at varying scales and densities. In three chronic ...[more]
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