Dataset Information

Salivary Periodontopathic Bacteria in Children and Adolescents with Down Syndrome.

ABSTRACT:

Objective

To assess and compare salivary periodontopathic bacteria between groups of Down syndrome and non-Down syndrome children and adolescents.

Materials and methods

This study included a sample of 30 Down syndrome children and adolescents (G-DS) and 30 age- and sex-matched non-Down syndrome subjects (G-ND). Clinical examination determined the gingival bleeding index (GBI) and plaque index. Unstimulated whole saliva samples were collected from all participants. The fluorescence in situ hybridization (FISH) technique identified the presence and density of eight periodontopathic bacteria in saliva. The statistical analysis included chi-square and Mann-Whitney U tests.

Results

In the G-DS group, bleeding on probing was more frequent (p = 0.037) and higher densities of Campylobacter rectus (p = 0.013), Porphyromonas gingivalis (p = 0.025), Treponema denticola (p = 0.026), Fusobacterium nucleatum (p = 0.013), Prevotella intermedia (p = 0.001) and Prevotella nigrescens (p = 0.008) were observed. Besides, in the G-DS, the densities of bacteria from the orange complex were significantly higher in the age group 3-7 years for F. nucleatum (p = 0.029), P. intermedia (p = 0.001) and P. nigrescens (p = 0.006). C. rectus was higher in the age group 8-12 years (p = 0.045).

Conclusion

The results showed that children and adolescents with Down syndrome have higher susceptibility to periodontal disease and number of periodontopathic bacteria.

SUBMITTER: Faria Carrada C

PROVIDER: S-EPMC5058504 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Publications

Salivary Periodontopathic Bacteria in Children and Adolescents with Down Syndrome.

Faria Carrada Camila C Almeida Ribeiro Scalioni Flávia F Evangelista Cesar Dionéia D Lopes Devito Karina K Ribeiro Luiz Cláudio LC Almeida Ribeiro Rosangela R

PloS one 20161011 10

<h4>Objective</h4>To assess and compare salivary periodontopathic bacteria between groups of Down syndrome and non-Down syndrome children and adolescents.<h4>Materials and methods</h4>This study included a sample of 30 Down syndrome children and adolescents (G-DS) and 30 age- and sex-matched non-Down syndrome subjects (G-ND). Clinical examination determined the gingival bleeding index (GBI) and plaque index. Unstimulated whole saliva samples were collected from all participants. The fluorescence ...[more]

PMID: 27727287

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Project description:BACKGROUND:Children and adolescents with Down syndrome have a distinctive foot shape (such as wide and flat feet) that often leads to difficulty with footwear fitting. 3-dimensional (3D) scanning can accurately measure the foot dimensions of individuals with Down syndrome, which may assist shoe fit. However, the reproducibility of measuring foot dimensions using 3D scans in children and adolescents with Down syndrome is unknown. The aim of this study was to determine the intra- and inter-rater reproducibility of measuring foot dimensions of children and adolescents with Down syndrome using 3D scanning. METHODS:3D foot scans of 30 participants with Down syndrome aged 5 to 17?years were obtained using the FotoScan 3D scanner. Foot dimensions assessed were foot length, ball of foot length, outside ball of foot length, diagonal foot width, horizontal foot width, heel width, ball girth, instep girth, first and fifth toe height, and instep height. Additionally, the Wesjflog Index and forefoot shape were determined. Measurements were completed by two raters independently on two separate occasions, 2 weeks apart. Intra- and inter-rater reliability were assessed using intra-class correlation coefficients (ICCs) and Gwet's AC1 statistics with 95% confidence intervals. Agreement was determined by calculating limits of agreement (LOA) and percentage agreement. RESULTS:Eighteen participants were female and 12 were male (mean age 10.6 [3.9] years). Intra-rater reproducibility (ICCs ranged from 0.74 to 0.99, 95% LOA from -?13.7?mm to 16.3?mm) and inter-rater reproducibility (ICCs ranging from 0.73 to 0.99, 95% LOA from -?18.8?mm to 12.7?mm) was good to excellent, although some measurements (ball of foot length, outside ball of foot length, heel width and girth measurements) displayed wider LOAs indicating relatively poorer agreement. Forefoot shape displayed substantial to almost perfect reliability (Gwet's AC1 0.68 to 0.85) and percentage agreement ranged from 73 to 87%, indicating acceptable agreement. CONCLUSIONS:The measurement of specific foot dimensions of children and adolescents with Down syndrome using 3D scans is reproducible. Findings of this study may be used to support future research measuring specific foot dimensions of children and adolescents with Down syndrome using 3D foot scans.

Dataset Information

Salivary Periodontopathic Bacteria in Children and Adolescents with Down Syndrome.

Objective

Materials and methods

Results

Conclusion

Publications

Salivary Periodontopathic Bacteria in Children and Adolescents with Down Syndrome.

Similar Datasets

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