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Salivary Periodontopathic Bacteria in Children and Adolescents with Down Syndrome.


ABSTRACT:

Objective

To assess and compare salivary periodontopathic bacteria between groups of Down syndrome and non-Down syndrome children and adolescents.

Materials and methods

This study included a sample of 30 Down syndrome children and adolescents (G-DS) and 30 age- and sex-matched non-Down syndrome subjects (G-ND). Clinical examination determined the gingival bleeding index (GBI) and plaque index. Unstimulated whole saliva samples were collected from all participants. The fluorescence in situ hybridization (FISH) technique identified the presence and density of eight periodontopathic bacteria in saliva. The statistical analysis included chi-square and Mann-Whitney U tests.

Results

In the G-DS group, bleeding on probing was more frequent (p = 0.037) and higher densities of Campylobacter rectus (p = 0.013), Porphyromonas gingivalis (p = 0.025), Treponema denticola (p = 0.026), Fusobacterium nucleatum (p = 0.013), Prevotella intermedia (p = 0.001) and Prevotella nigrescens (p = 0.008) were observed. Besides, in the G-DS, the densities of bacteria from the orange complex were significantly higher in the age group 3-7 years for F. nucleatum (p = 0.029), P. intermedia (p = 0.001) and P. nigrescens (p = 0.006). C. rectus was higher in the age group 8-12 years (p = 0.045).

Conclusion

The results showed that children and adolescents with Down syndrome have higher susceptibility to periodontal disease and number of periodontopathic bacteria.

SUBMITTER: Faria Carrada C 

PROVIDER: S-EPMC5058504 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Publications

Salivary Periodontopathic Bacteria in Children and Adolescents with Down Syndrome.

Faria Carrada Camila C   Almeida Ribeiro Scalioni Flávia F   Evangelista Cesar Dionéia D   Lopes Devito Karina K   Ribeiro Luiz Cláudio LC   Almeida Ribeiro Rosangela R  

PloS one 20161011 10


<h4>Objective</h4>To assess and compare salivary periodontopathic bacteria between groups of Down syndrome and non-Down syndrome children and adolescents.<h4>Materials and methods</h4>This study included a sample of 30 Down syndrome children and adolescents (G-DS) and 30 age- and sex-matched non-Down syndrome subjects (G-ND). Clinical examination determined the gingival bleeding index (GBI) and plaque index. Unstimulated whole saliva samples were collected from all participants. The fluorescence  ...[more]

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