Ontology highlight
ABSTRACT:
SUBMITTER: Wang ZR
PROVIDER: S-EPMC5058774 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Wang Zong-Ren ZR Wei Jin-Huan JH Zhou Jian-Cheng JC Haddad Ahmed A Zhao Liang-Yun LY Kapur Payal P Wu Kai-Jie KJ Wang Bin B Yu Yan-Hong YH Liao Bing B He Da-Lin DL Chen Wei W Margulis Vitaly V Hsieh Jer-Tsong JT Luo Jun-Hang JH
Oncotarget 20160501 21
We have recently reported tumor suppressive role of DAB2IP in RCC development. In this study, We identified one CpG methylation biomarker (DAB2IP CpG1) located UTSS of DAB2IP that was associated with poor overall survival in a cohort of 318 ccRCC patients from the Cancer Genome Atlas (TCGA). We further validated the prognostic accuracy of DAB2IP CpG methylation by pyrosequencing quantitative methylation assay in 224 ccRCC patients from multiple Chinese centers (MCHC set), and 239 patients from U ...[more]