Ontology highlight
ABSTRACT:
SUBMITTER: Wong VK
PROVIDER: S-EPMC5059462 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Wong Vanessa K VK Baker Stephen S Connor Thomas R TR Pickard Derek D Page Andrew J AJ Dave Jayshree J Murphy Niamh N Holliman Richard R Sefton Armine A Millar Michael M Dyson Zoe A ZA Dougan Gordon G Holt Kathryn E KE
Nature communications 20161005
The population of Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever, exhibits limited DNA sequence variation, which complicates efforts to rationally discriminate individual isolates. Here we utilize data from whole-genome sequences (WGS) of nearly 2,000 isolates sourced from over 60 countries to generate a robust genotyping scheme that is phylogenetically informative and compatible with a range of assays. These data show that, with the exception of the rapidly d ...[more]