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Refractive Errors and Concomitant Strabismus: A Systematic Review and Meta-analysis.


ABSTRACT: This systematic review and meta-analysis is to evaluate the risk of development of concomitant strabismus due to refractive errors. Eligible studies published from 1946 to April 1, 2016 were identified from MEDLINE and EMBASE that evaluated any kinds of refractive errors (myopia, hyperopia, astigmatism and anisometropia) as an independent factor for concomitant exotropia and concomitant esotropia. Totally 5065 published records were retrieved for screening, 157 of them eligible for detailed evaluation. Finally 7 population-based studies involving 23,541 study subjects met our criteria for meta-analysis. The combined OR showed that myopia was a risk factor for exotropia (OR: 5.23, P?=?0.0001). We found hyperopia had a dose-related effect for esotropia (OR for a spherical equivalent [SE] of 2-3 diopters [D]: 10.16, P?=?0.01; OR for an SE of 3-4D: 17.83, P?

SUBMITTER: Tang SM 

PROVIDER: S-EPMC5059633 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature

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Refractive Errors and Concomitant Strabismus: A Systematic Review and Meta-analysis.

Tang Shu Min SM   Chan Rachel Y T RY   Bin Lin Shi S   Rong Shi Song SS   Lau Henry H W HH   Lau Winnie W Y WW   Yip Wilson W K WW   Chen Li Jia LJ   Ko Simon T C ST   Yam Jason C S JC  

Scientific reports 20161012


This systematic review and meta-analysis is to evaluate the risk of development of concomitant strabismus due to refractive errors. Eligible studies published from 1946 to April 1, 2016 were identified from MEDLINE and EMBASE that evaluated any kinds of refractive errors (myopia, hyperopia, astigmatism and anisometropia) as an independent factor for concomitant exotropia and concomitant esotropia. Totally 5065 published records were retrieved for screening, 157 of them eligible for detailed eval  ...[more]

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