Ontology highlight
ABSTRACT:
SUBMITTER: Silvola JM
PROVIDER: S-EPMC5059718 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Silvola Johanna M U JM Virtanen Helena H Siitonen Riikka R Hellberg Sanna S Liljenbäck Heidi H Metsälä Olli O Ståhle Mia M Saanijoki Tiina T Käkelä Meeri M Hakovirta Harri H Ylä-Herttuala Seppo S Saukko Pekka P Jauhiainen Matti M Veres Tibor Z TZ Jalkanen Sirpa S Knuuti Juhani J Saraste Antti A Roivainen Anne A
Scientific reports 20161012
Given the important role of inflammation and the potential association of the leukocyte trafficking-associated adhesion molecule vascular adhesion protein 1 (VAP-1) with atherosclerosis, this study examined whether functional VAP-1 is expressed in atherosclerotic lesions and, if so, whether it could be targeted by positron emission tomography (PET). First, immunohistochemistry revealed that VAP-1 localized to endothelial cells of intra-plaque neovessels in human carotid endarterectomy samples fr ...[more]