Ontology highlight
ABSTRACT:
SUBMITTER: Byarugaba DK
PROVIDER: S-EPMC5059949 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Byarugaba Denis K DK Erima Bernard B Millard Monica M Kibuuka Hannah H Lkwago Luswa L Bwogi Josephine J Mimbe Derrick D Kiconco Jocelyn B JB Tugume Titus T Mworozi Edison A EA Turner Jasmine J Mckenzie Pamela P PP Webby Richard R J RR Webster Robert G RG Foret Charlotte C Ducatez Mariette F MF Coldren Rodney R Wabwire-Mangen Fred F Krauss Scott S
Influenza and other respiratory viruses 20160719 6
We report a whole-genome analysis of 19 influenza A(H1N1)pdm09 isolates from four Ugandan hospitals between 2009 and 2011. The isolates differed from the vaccine strain A/California/07/2009 by three amino acid substitutions P100S, S220T, and I338V in the hemagglutinin and by two amino acid substitutions V106I and N248D in the neuraminidase proteins with consistent mutations in all gene segments distinguishing isolates from the 2009/2010 to 2010/2011 seasons. Phylogenetic analysis showed low gene ...[more]