Near-Infrared Intraoperative Chemiluminescence Imaging.
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ABSTRACT:
SUBMITTER: Buchel GE
PROVIDER: S-EPMC5061038 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Publications
Near-Infrared Intraoperative Chemiluminescence Imaging.
Büchel Gabriel E GE Carney Brandon B Shaffer Travis M TM Tang Jun J Austin Christine C Arora Manish M Zeglis Brian M BM Grimm Jan J Eppinger Jörg J Reiner Thomas T
ChemMedChem 20160729 18
Intraoperative imaging technologies recently entered the operating room, and their implementation is revolutionizing how physicians plan, monitor, and perform surgical interventions. In this work, we present a novel surgical imaging reporter system: intraoperative chemiluminescence imaging (ICI). To this end, we have leveraged the ability of a chemiluminescent metal complex to generate near-infrared light upon exposure to an aqueous solution of Ce(4+) in the presence of reducing tissue or blood ...[more]
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