Ontology highlight
ABSTRACT:
SUBMITTER: Cusanovich DA
PROVIDER: S-EPMC5062579 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Cusanovich Darren A DA Caliskan Minal M Billstrand Christine C Michelini Katelyn K Chavarria Claudia C De Leon Sherryl S Mitrano Amy A Lewellyn Noah N Elias Jack A JA Chupp Geoffrey L GL Lang Roberto M RM Shah Sanjiv J SJ Decara Jeanne M JM Gilad Yoav Y Ober Carole C
Human molecular genetics 20160229 10
Genome-wide association studies (GWASs) have become a standard tool for dissecting genetic contributions to disease risk. However, these studies typically require extraordinarily large sample sizes to be adequately powered. Strategies that incorporate functional information alongside genetic associations have proved successful in increasing GWAS power. Following this paradigm, we present the results of 20 different genetic association studies for quantitative traits related to complex diseases, ...[more]