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Schistosoma mansoni in Gabon: Emerging or Ignored?


ABSTRACT: Schistosomiasis affects millions of people across Africa. We detected eggs of Schistosoma mansoni in western lowland gorilla and central chimpanzee fecal samples in Loango National Park, Gabon. We analyzed nuclear and mitochondrial DNA, namely internal transcribed spacer and cytochrome c oxidase subunit 1 fragments, and the resulting maximum likelihood phylogenetic analyses and haplotype network of the ITS and COI, respectively, showed that the samples from gorillas and chimpanzees clustered clearly within the S. mansoni clade. This is the first confirmed record of S. mansoni from Gabon, which urges surveillance in the area and prompts questions regarding the extent of zoonotic transmission and the clinical impact.

SUBMITTER: Cervena B 

PROVIDER: S-EPMC5062786 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature

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Schistosoma mansoni in Gabon: Emerging or Ignored?

Červená Barbora B   Brant Sara Vanessa SV   Fairet Emilie E   Shirley Matthew H MH   Petrželková Klára Judita KJ   Modrý David D  

The American journal of tropical medicine and hygiene 20160808 4


Schistosomiasis affects millions of people across Africa. We detected eggs of Schistosoma mansoni in western lowland gorilla and central chimpanzee fecal samples in Loango National Park, Gabon. We analyzed nuclear and mitochondrial DNA, namely internal transcribed spacer and cytochrome c oxidase subunit 1 fragments, and the resulting maximum likelihood phylogenetic analyses and haplotype network of the ITS and COI, respectively, showed that the samples from gorillas and chimpanzees clustered cle  ...[more]

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