Ontology highlight
ABSTRACT:
SUBMITTER: van Bergeijk P
PROVIDER: S-EPMC5063096 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
van Bergeijk Petra P Adrian Max M Hoogenraad Casper C CC Kapitein Lukas C LC
Nature 20150107 7537
Proper positioning of organelles by cytoskeleton-based motor proteins underlies cellular events such as signalling, polarization and growth. For many organelles, however, the precise connection between position and function has remained unclear, because strategies to control intracellular organelle positioning with spatiotemporal precision are lacking. Here we establish optical control of intracellular transport by using light-sensitive heterodimerization to recruit specific cytoskeletal motor p ...[more]