Restoration of Corneal Transparency by Mesenchymal Stem Cells.
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ABSTRACT:
SUBMITTER: Mittal SK
PROVIDER: S-EPMC5063582 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
Restoration of Corneal Transparency by Mesenchymal Stem Cells.
Mittal Sharad K SK Omoto Masahiro M Amouzegar Afsaneh A Sahu Anuradha A Rezazadeh Alexandra A Katikireddy Kishore R KR Shah Dhvanit I DI Sahu Srikant K SK Chauhan Sunil K SK
Stem cell reports 20160929 4
Transparency of the cornea is indispensable for optimal vision. Ocular trauma is a leading cause of corneal opacity, leading to 25 million cases of blindness annually. Recently, mesenchymal stem cells (MSCs) have gained prominence due to their inflammation-suppressing and tissue repair functions. Here, we investigate the potential of MSCs to restore corneal transparency following ocular injury. Using an in vivo mouse model of ocular injury, we report that MSCs have the capacity to restore cornea ...[more]
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