Ontology highlight
ABSTRACT:
SUBMITTER: Wu T
PROVIDER: S-EPMC5064389 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Wu Tao T Heuillard Emilie E Lindner Véronique V Bou About Ghina G Ignat Mihaela M Dillenseger Jean-Philippe JP Anton Nicolas N Dalimier Eugénie E Gossé Francine F Fouré Gael G Blindauer Franck F Giraudeau Céline C El-Saghire Hussein H Bouhadjar Mourad M Calligaro Cynthia C Sorg Tania T Choquet Philippe P Vandamme Thierry T Ferrand Christophe C Marescaux Jacques J Baumert Thomas F TF Diana Michele M Pessaux Patrick P Robinet Eric E
Scientific reports 20161014
The development of multimodal strategies for the treatment of hepatocellular carcinoma requires tractable animal models allowing for advanced in vivo imaging. Here, we characterize an orthotopic hepatocellular carcinoma model based on the injection of luciferase-expressing human hepatoma Huh-7 (Huh-7-Luc) cells in immunodeficient mice. Luciferase allows for an easy repeated monitoring of tumor growth by in vivo bioluminescence. The intrahepatic injection was more efficient than intrasplenic or i ...[more]