Ontology highlight
ABSTRACT:
SUBMITTER: Lin JB
PROVIDER: S-EPMC5065746 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Lin Jenny B JB Poh Scott S Panitch Alyssa A
Nanomedicine : nanotechnology, biology, and medicine 20160527 7
Characterized by pain, cartilage degradation, and inflammation, osteoarthritis is often treated with anti-inflammatory therapies that provide short-term relief but can have adverse side effects; intra-articular drug delivery systems with controlled release of anti-inflammatory peptides using degradable poly(N-isopropylacrylamide) (pNIPAM) nanoparticles could prolong relief and minimize these side effects. Nanoparticles provide a biocompatible drug carrier that can protect encapsulated therapeuti ...[more]