Ontology highlight
ABSTRACT:
SUBMITTER: Zibelman M
PROVIDER: S-EPMC5066115 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Zibelman Matthew M Plimack Elizabeth R ER
Future oncology (London, England) 20160712 19
Systemic therapy for bladder cancer, both localized muscle-invasive disease and metastatic disease, has seen minimal progress over the past two decades. Current approaches rely upon cytotoxic chemotherapy combinations aimed at increasing cure rates or achieving palliation and disease control, but these regimens are fraught with short- and long-term toxicities and outcomes remain suboptimal. The emergence of systemic immunotherapies that can provide durable remissions in subsets of patients with ...[more]