Exocrine pancreatic function in children with Alagille syndrome.
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ABSTRACT:
SUBMITTER: Gliwicz D
PROVIDER: S-EPMC5066201 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
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Exocrine pancreatic function in children with Alagille syndrome.
Gliwicz Dorota D Jankowska Irena I Wierzbicka Aldona A Miśkiewicz-Chotnicka Anna A Lisowska Aleksandra A Walkowiak Jarosław J
Scientific reports 20161017
Alagille syndrome (AGS) is often associated with symptoms of maldigestion, such as steatorrhea, hypotrophy and growth retardation. Exocrine pancreatic insufficiency was proposed as the underlying cause. We aimed to assess the exocrine pancreatic function with the use of different methods in AGS patients. Concentrations of fecal elastase-1 (FE1) and fecal lipase (FL) activities were measured in 33 children with AGS. The C-mixed triglyceride breath test (MTBT) in a subgroup comprising 15 patients. ...[more]
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