Ontology highlight
ABSTRACT:
SUBMITTER: Gillespie JW
PROVIDER: S-EPMC5066567 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Combinatorial chemistry & high throughput screening 20160101 5
Cancer cell-specific diagnostic or therapeutic tools are commonly believed to significantly increase the success rate of cancer diagnosis and targeted therapies. To extend the repertoire of available cancer cell-specific phage fusion proteins and study their efficacy as navigating moieties, we used two landscape phage display libraries f8/8 and f8/9 displaying an 8- or 9-mer random peptide fusion to identify a panel of novel peptide families that are specific to Calu-3 cells. Using a phage captu ...[more]