Ontology highlight
ABSTRACT:
SUBMITTER: Dalal CK
PROVIDER: S-EPMC5067116 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Dalal Chiraj K CK Zuleta Ignacio A IA Mitchell Kaitlin F KF Andes David R DR El-Samad Hana H Johnson Alexander D AD
eLife 20160910
Evolutionary changes in transcription networks are an important source of diversity across species, yet the quantitative consequences of network evolution have rarely been studied. Here we consider the transcriptional 'rewiring' of the three <i>GAL</i> genes that encode the enzymes needed for cells to convert galactose to glucose. In <i>Saccharomyces cerevisiae</i>, the transcriptional regulator Gal4 binds and activates these genes. In the human pathogen <i>Candida albicans</i> (which last share ...[more]