Ontology highlight
ABSTRACT:
SUBMITTER: Liu Y
PROVIDER: S-EPMC5068228 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Liu Yue Y Wang Ting-Ting TT Zhang Ran R Fu Wen-Yan WY Wang Xu X Wang Fang F Gao Peng P Ding Yang-Nan YN Xie Yan Y Hao De-Long DL Chen Hou-Zao HZ Liu De-Pei DP
The Journal of experimental medicine 20160926 11
Abdominal aortic aneurysm (AAA), characterized by a localized dilation of the abdominal aorta, is a life-threatening vascular pathology. Because of the current lack of effective treatment for AAA rupture, prevention is of prime importance for AAA management. Calorie restriction (CR) is a nonpharmacological intervention that delays the aging process and provides various health benefits. However, whether CR prevents AAA formation remains untested. In this study, we subjected Apoe<sup>-/-</sup> mic ...[more]