Ontology highlight
ABSTRACT:
SUBMITTER: Kabytaev K
PROVIDER: S-EPMC5068909 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Kabytaev Kuanysh K Connolly Shawn S Rohlfing Curt L CL Sacks David B DB Stoyanov Alexander V AV Little Randie R RR
Clinica chimica acta; international journal of clinical chemistry 20160422
<h4>Background</h4>Glycated hemoglobin (GHb), reported as HbA1c, is used as marker of long-term glycemia for diabetic patients. HbA1c results from boronate affinity methods are generally considered to be unaffected by most hemoglobin variants; this assumes comparable glycation of variant and non-variant (HbAA) hemoglobins. In this report, glycation of HbA beta chain (βA) and HbS beta chain (βS) for the most common Hb variant trait (HbAS) are examined.<h4>Methods</h4>We analyzed 41 blood samples ...[more]