The fate of medications evaluated for ischemic stroke pharmacotherapy over the period 1995-2015.
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ABSTRACT:
SUBMITTER: Chen X
PROVIDER: S-EPMC5071630 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Publications
The fate of medications evaluated for ischemic stroke pharmacotherapy over the period 1995-2015.
Acta pharmaceutica Sinica. B 20160728 6
Stroke is a brain damage caused by a loss of blood supply to a portion of the brain, which requires prompt and effective treatment. The current pharmacotherapy for ischemic stroke primarily relies on thrombolysis using recombinant tissue plasminogen activators (rt-PAs) to breakdown blood clots. Neuroprotective agents that inhibit excitatory neurotransmitters are also used to treat ischemic stroke but have failed to translate into clinical benefits. This poses a major challenge in biomedical rese ...[more]
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