Ontology highlight
ABSTRACT:
SUBMITTER: Postel S
PROVIDER: S-EPMC5072837 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Postel Sandra S Deredge Daniel D Bonsor Daniel A DA Yu Xiong X Diederichs Kay K Helmsing Saskia S Vromen Aviv A Friedler Assaf A Hust Michael M Egelman Edward H EH Beckett Dorothy D Wintrode Patrick L PL Sundberg Eric J EJ
eLife 20160924
Flagella are crucial for bacterial motility and pathogenesis. The flagellar capping protein (FliD) regulates filament assembly by chaperoning and sorting flagellin (FliC) proteins after they traverse the hollow filament and exit the growing flagellum tip. In the absence of FliD, flagella are not formed, resulting in impaired motility and infectivity. Here, we report the 2.2 Å resolution X-ray crystal structure of FliD from <i>Pseudomonas aeruginosa</i>, the first high-resolution structure of any ...[more]