Plasma miR-19b and miR-183 as Potential Biomarkers of Lung Cancer.
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ABSTRACT:
SUBMITTER: Zaporozhchenko IA
PROVIDER: S-EPMC5074500 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Plasma miR-19b and miR-183 as Potential Biomarkers of Lung Cancer.
Zaporozhchenko Ivan A IA Morozkin Evgeny S ES Skvortsova Tatyana E TE Ponomaryova Anastasia A AA Rykova Elena Yu EY Cherdyntseva Nadezhda V NV Polovnikov Evgeny S ES Pashkovskaya Oksana A OA Pokushalov Evgeny A EA Vlassov Valentin V VV Laktionov Pavel P PP
PloS one 20161021 10
Lung cancer is a complex disease that often manifests at the point when treatment is not effective. Introduction of blood-based complementary diagnostics using molecular markers may enhance early detection of this disease and help reduce the burden of lung cancer. Here we evaluated the diagnostic potential of seven plasma miRNA biomarkers (miR-21, -19b, -126, -25, -205, -183, -125b) by quantitative reverse transcription PCR. Influence clinical and demographical characteristics, including age, tu ...[more]
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