Ontology highlight
ABSTRACT:
SUBMITTER: Zampini V
PROVIDER: S-EPMC5074806 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Zampini Valeria V Liu Jian K JK Diana Marco A MA Maldonado Paloma P PP Brunel Nicolas N Dieudonné Stéphane S
eLife 20160919
Synaptic currents display a large degree of heterogeneity of their temporal characteristics, but the functional role of such heterogeneities remains unknown. We investigated in rat cerebellar slices synaptic currents in Unipolar Brush Cells (UBCs), which generate intrinsic mossy fibers relaying vestibular inputs to the cerebellar cortex. We show that UBCs respond to sinusoidal modulations of their sensory input with heterogeneous amplitudes and phase shifts. Experiments and modeling indicate tha ...[more]