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IncHI2 Plasmids Are the Key Vectors Responsible for oqxAB Transmission among Salmonella Species.

ABSTRACT: This study reported and analyzed the complete sequences of two oqxAB-bearing IncHI2 plasmids harbored by a clinical Salmonella enterica serovar Typhimurium strain and an S Indiana strain of animal origin, respectively. In particular, pA3T recovered from S Indiana comprised the resistance determinants oqxAB, aac(6')Ib-cr, fosA3, and blaCTX-M-14 Further genetic screening of 63 oqxAB-positive Salmonella isolates revealed that the majority carried IncHI2 plasmids, confirming that such plasmids play a pivotal role in dissemination of oqxAB in Salmonella spp.

SUBMITTER: Wong MH 

PROVIDER: S-EPMC5075106 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature

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IncHI2 Plasmids Are the Key Vectors Responsible for oqxAB Transmission among Salmonella Species.

Wong Marcus Ho-Yin MH   Chan Edward Wai-Chi EW   Xie Liqi L   Li Ruichao R   Chen Sheng S  

Antimicrobial agents and chemotherapy 20161021 11

This study reported and analyzed the complete sequences of two oqxAB-bearing IncHI2 plasmids harbored by a clinical Salmonella enterica serovar Typhimurium strain and an S Indiana strain of animal origin, respectively. In particular, pA3T recovered from S Indiana comprised the resistance determinants oqxAB, aac(6')Ib-cr, fosA3, and bla<sub>CTX-M-14</sub> Further genetic screening of 63 oqxAB-positive Salmonella isolates revealed that the majority carried IncHI2 plasmids, confirming that such pla  ...[more]

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