Ontology highlight
ABSTRACT:
SUBMITTER: Hellmich UA
PROVIDER: S-EPMC5075240 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Hellmich Ute A UA Gaudet Rachelle R
Handbook of experimental pharmacology 20140101
Membrane proteins remain challenging targets for structural biologists, despite recent technical developments regarding sample preparation and structure determination. We review recent progress towards a structural understanding of TRP channels and the techniques used to that end. We discuss available low-resolution structures from electron microscopy (EM), X-ray crystallography, and nuclear magnetic resonance (NMR) and review the resulting insights into TRP channel function for various subfamil ...[more]