Ontology highlight
ABSTRACT:
SUBMITTER: Shi Y
PROVIDER: S-EPMC5076792 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Shi Yulu Y Thrippleton Michael J MJ Makin Stephen D SD Marshall Ian I Geerlings Mirjam I MI de Craen Anton J M AJM van Buchem Mark A MA Wardlaw Joanna M JM
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20160805 10
White matter hyperintensities are frequent on neuroimaging of older people and are a key feature of cerebral small vessel disease. They are commonly attributed to chronic hypoperfusion, although whether low cerebral blood flow is cause or effect is unclear. We systematically reviewed studies that assessed cerebral blood flow in small vessel disease patients, performed meta-analysis and sensitivity analysis of potential confounders. Thirty-eight studies (n = 4006) met the inclusion criteria, incl ...[more]