Ontology highlight
ABSTRACT:
SUBMITTER: Hanus C
PROVIDER: S-EPMC5077297 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Hanus Cyril C Geptin Helene H Tushev Georgi G Garg Sakshi S Alvarez-Castelao Beatriz B Sambandan Sivakumar S Kochen Lisa L Hafner Anne-Sophie AS Langer Julian D JD Schuman Erin M EM
eLife 20160928
N-glycosylation - the sequential addition of complex sugars to adhesion proteins, neurotransmitter receptors, ion channels and secreted trophic factors as they progress through the endoplasmic reticulum and the Golgi apparatus - is one of the most frequent protein modifications. In mammals, most organ-specific N-glycosylation events occur in the brain. Yet, little is known about the nature, function and regulation of N-glycosylation in neurons. Using imaging, quantitative immunoblotting and mass ...[more]