Ontology highlight
ABSTRACT:
SUBMITTER: Gelbard A
PROVIDER: S-EPMC5077677 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Gelbard Alexander A Katsantonis Nicolas-George NG Mizuta Masanobu M Newcomb Dawn D Rotsinger Joseph J Rousseau Bernard B Daniero James J JJ Edell Eric S ES Ekbom Dale C DC Kasperbauer Jan L JL Hillel Alexander T AT Yang Liying L Garrett C Gaelyn CG Netterville James L JL Wootten Christopher T CT Francis David O DO Stratton Charles C Jenkins Kevin K McGregor Tracy L TL Gaddy Jennifer A JA Blackwell Timothy S TS Drake Wonder P WP
The Laryngoscope 20160614 11
<h4>Objectives/hypothesis</h4>Idiopathic subglottic stenosis (iSGS) is a rare and devastating extrathoracic obstruction involving the lower laryngeal and upper tracheal airway. It arises without known antecedent injury or associated disease process. Persistent mucosal inflammation and a localized fibrotic response are hallmarks of the disease. Despite the initial clinical description of iSGS more than 40 year ago, there have been no substantive investigations into the pathogenesis of this enigma ...[more]