Ontology highlight
ABSTRACT:
SUBMITTER: Oresic M
PROVIDER: S-EPMC5078571 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Orešič Matej M Posti Jussi P JP Kamstrup-Nielsen Maja H MH Takala Riikka S K RSK Lingsma Hester F HF Mattila Ismo I Jäntti Sirkku S Katila Ari J AJ Carpenter Keri L H KLH Ala-Seppälä Henna H Kyllönen Anna A Maanpää Henna-Riikka HR Tallus Jussi J Coles Jonathan P JP Heino Iiro I Frantzén Janek J Hutchinson Peter J PJ Menon David K DK Tenovuo Olli O Hyötyläinen Tuulia T
EBioMedicine 20160715
Traumatic brain injury (TBI) is a major cause of death and disability worldwide, especially in children and young adults. TBI is an example of a medical condition where there are still major lacks in diagnostics and outcome prediction. Here we apply comprehensive metabolic profiling of serum samples from TBI patients and controls in two independent cohorts. The discovery study included 144 TBI patients, with the samples taken at the time of hospitalization. The patients were diagnosed as severe ...[more]