Ontology highlight
ABSTRACT:
SUBMITTER: Kalkhof S
PROVIDER: S-EPMC5079110 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Proteins 20101011 16
Basement membranes are thin extracellular protein layers, which separate endothelial and epithelial cells from the underlying connecting tissue. The main noncollagenous components of basement membranes are laminins, trimeric glycoproteins, which form polymeric networks by interactions of their N-terminal (LN) domains; however, no high-resolution structure of laminin LN domains exists so far. To construct models for laminin β(1) and γ(1) LN domains, 14 potentially suited template structures were ...[more]