Effects of Sodium Restriction on Activation of the Renin-Angiotensin-Aldosterone System and Immune Indices During HIV Infection.
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ABSTRACT:
SUBMITTER: Srinivasa S
PROVIDER: S-EPMC5079375 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
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Effects of Sodium Restriction on Activation of the Renin-Angiotensin-Aldosterone System and Immune Indices During HIV Infection.
Srinivasa Suman S Burdo Tricia H TH Williams Kenneth C KC Mitten Emilie K EK Wong Kimberly K Fitch Kathleen V KV Stanley Takara T Adler Gail K GK Grinspoon Steven K SK
The Journal of infectious diseases 20160822 9
<h4>Background</h4> Human immunodeficiency virus (HIV)-infected patients demonstrate increased activation of the renin-angiotensin-aldosterone system (RAAS). We evaluated changes in immune markers with physiological RAAS activation.<h4>Methods</h4> Immune activation markers were assessed serially in 18 HIV-infected and 7 non-HIV-infected subjects consuming an ad libitum diet followed by a standardized low-sodium diet.<h4>Results</h4> Levels of CCL-2 (P = .0004) and soluble CD163 (P = .0001) sign ...[more]
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