Melody discrimination and protein fold classification.
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ABSTRACT:
SUBMITTER: Bywater RP
PROVIDER: S-EPMC5079661 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
Melody discrimination and protein fold classification.
Bywater Robert P RP Middleton Jonathan N JN
Heliyon 20161020 10
One of the greatest challenges in theoretical biophysics and bioinformatics is the identification of protein folds from sequence data. This can be regarded as a pattern recognition problem. In this paper we report the use of a melody generation software where the inputs are derived from calculations of evolutionary information, secondary structure, flexibility, hydropathy and solvent accessibility from multiple sequence alignment data. The melodies so generated are derived from the sequence, and ...[more]
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