Ontology highlight
ABSTRACT:
SUBMITTER: Cruz GI
PROVIDER: S-EPMC5079818 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Cruz Giovanna I GI Shao Xiaorong X Quach Hong H Ho Kimberly A KA Sterba Kirsten K Noble Janelle A JA Patsopoulos Nikolaos A NA Busch Michael P MP Triulzi Darrell J DJ Wong Wendy S W WS Solomon Benjamin D BD Niederhuber John E JE Criswell Lindsey A LA Barcellos Lisa F LF
Journal of autoimmunity 20160704
Systemic lupus erythematosus (SLE) disproportionately affects women of reproductive age. During pregnancy, women are exposed to various sources of fetal material possibly constituting a significant immunologic exposure relevant to the development of SLE. The objective of this study was to investigate whether having any children who carry DRB1 alleles associated with SLE increase the risk of maternal SLE. This case-control study is based on the University of California, San Francisco Mother-Child ...[more]